That was the request of Martin Shkreli, former CEO of the famous pharmaceutical company Turing Pharmaceuticals, who is currently serving a 20-year sentence for fraud.
Martin Shkreli, former CEO of Turing Pharmaceuticals, who is currently serving a 20-year sentence for fraud, is still working with his team to implement scientific projects to develop a treatment for the SARS-CoV-2 virus.
According to Shkreli, the efforts of other scientists to study the vaccine and the Covid-19 remedy are not enough.
According to documents published by biotechnology firm Prospero, Shkreli said he was one of the few executives with experience in all aspects of drug development.
Martin Shkreli identifies himself as one of the few executives with experience in all aspects of drug development. Photo: Arstechnica.
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"From molecular creation, hypothesis development to preclinical evaluation, clinical trial design, production and distribution globally, I can do it all smoothly," Shkreli wrote in his book. Whether.
Shkreli also requested a temporary 3-month prison term to support research into SARS-CoV-2 treatment. He said he wanted to contribute to the current bad situation, not for his own freedom.
In the remainder of the paper, Shkreli and his colleagues reported that they identified the ingredients for corona antiviral drugs using a computer model based on the available compound. Based on that model, Shkreli and his team could find a compound that kills the main enzyme in SARS-CoV-2.
The main enzyme in the Shkreli group's target is RNA polymerase-dependent RNA. This is the main component that SARS-CoV-2 uses to make copies of its own genetic material.
Antiviral drugs, such as the "emerging drug" Remdesivir, also contain ingredients that can inhibit this polymerase.
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Martin Shkreli, former CEO of Turing Pharmaceuticals, who is serving a 20-year sentence for fraud. Photo: Insider.
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The Shkreli team said it found eight existing drugs that could block SARS-CoV-2. Leading the list is Clofazimine, an antibiotic used to treat leprosy.
Various projects are being carried out by the research team. This includes the design of analogues for highly valued compounds such as clofazimine by various computational methods.
According to the famous pharmaceutical chemist and industrial blogger Derek Lowe, the project of the Shkreli team is completely "not crazy and very applicable".
Martin Shkreli was once called "America's most hated man". He was famous for the shocking shock in the world pharmaceutical industry when raising the price of the important drug Daraprim to 5,000% after just one night. On August 4, 2017, Shkreli was sentenced to cheat investors in two hedge funds and received a 20-year sentence.